Fig. 3
From: A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens
Expression pattern of TRIOBP in the human cochlea. A SR-SIM image that illustrates TRIOBP expression in the organ of Corti. Expression is present in inner and outer hair cell bodies, cuticula, stereocilia bundles, and nerve fibers. B Confocal microscopy of human spiral ganglion cell bodies expressing TRIOBP. Expression is not seen in the central axons. C Higher magnification shows TRIOBP expression in outer hair cell stereocilia and cuticula. D Corresponding image shows co-expression of actin and TRIOBP in the stereocilia bundle and cuticular plate. IHC = inner hair cell, OHCs = outer hair cells, n = afferent/efferent neurons, TUJ1 = neuron-specific class III beta-tubulin. Nuclei are stained with DAPI (blue)