Table 1 Baseline demographics and characteristics
Variables | Dexmedetomidine group (n = 251) | Placebo group (n = 257) | p |
|---|---|---|---|
Age, mean ± SD, years | 64.84 ± 6.14 | 64.57 ± 6.22 | 0.624 |
BMI, mean ± SD, kg/m2 | 24.98 ± 3.00 | 24.87 ± 3.26 | 0.695 |
Surgery classification, n (%) | 0.347 | ||
without CPB | 172(68.5%) | 166(64.6%) | |
With CPB | 79(31.5%) | 84(35.4%) | |
Men, n (%) | 166(66.1%) | 156(60.7%) | 0.204 |
Education, mean ± SD, years | 7.87±2.847 | 7.46±3.276 | 0.133 |
Hypertension, n (%) | 132(52.6%) | 134(52.1%) | 0.919 |
Diabetes, n (%) | 76(30.3%) | 77(30.0%) | 0.938 |
Renal failure, n (%) | 6(2.4%) | 5(1.9%) | 0.731 |
Infarction, n (%) | 40(15.9%) | 38(14.8%) | 0.719 |
Smoking, n (%) | 75(29.9%) | 89(34.6%) | 0.252 |
Alcohol, n (%) | 61(24.3%) | 60(23.3%) | 0.8 |
LVEF, n (%) | 0.692 | ||
≤ 40% | 12(4.8%) | 13(5.1%) | |
41–60% | 200(79.7%) | 197(76.7%) | |
≥ 61% | 39(15.5%) | 47(18.3%) | |
Atrial fibrillation before surgery | 13(5.2%) | 11(4.3%) | 0.633 |
SOFA score at 8 h after surgerya | 7.16 ± 3.1 | 7.12 ± 3.01 | 0.899 |
APACHE II at 8 h after surgeryb | 7.706 ± 2.15 | 7.63 ± 2.012 | 0.686 |
PSQI score at admission c | 7.1 ± 2.121 | 7.06 ± 2.161 | 0.844 |