Fig. 6
Multivariate HRs (95% CIs) for factors associated with treatment failure among initiators of SGLT2i with DKD (N = 6389). * Statistically significant (p value < 0.05) factors associated with a positive effect are in red and a negative effect are in green. Abbreviations: CI = confidence interval, DPP4i = dipeptidyl peptidase-4 inhibitor, GLP1ra = glucagon-like peptide-1 receptor agonist, HR = hazard ratio. Combined abbreviations for Additional Files: DPP4i = dipeptidyl peptidase-4 inhibitor, GLP1ra = glucagon-like peptide-1 receptor agonist, DKD = diabetic kidney disease, SGLT2i = sodium-glucose co-transporter-2 inhibitor, T2D = type 2 diabetes, CV = cardiovascular, CVD = Cardiovascular disease, ACEi = angiotensin-converting enzyme inhibitor, AKI = acute kidney injury, eGFR = Estimated glomerular filtration rate, ESKD = end-stage kidney disease, HbA1c = hemoglobin A1c, ICD = International Classifications of Diseases, NMSC = nonmelanoma skin cancer, UACR = urine albumin-to-creatinine ratio, NDC = National Drug Code