Rapid intrapartum test for maternal group B streptococcal colonisation and its effect on antibiotic use in labouring women with risk factors for early-onset neonatal infection (GBS2): cluster randomised trial with nested test accuracy study

Table 2 Effects of a rapid test for GBS on maternal exposure to antibiotics compared to usual care

Outcome	Rapid test, n (%)	Usual care, n (%)	Adjusted risk difference (95% CI)¹	Adjusted relative risk (95% CI)²
Maternal primary	(n = 722)	(n = 906)
IAP for GBS
Yes	297 (41%)	328 (36%)	0.05 (− 0.07, 0.18)	1.16 (0.83, 1.64)
No	419 (59%)	578 (64%)	0.05 (− 0.07, 0.18)	1.16 (0.83, 1.64)
Missing	6	0
Maternal secondary
IAP for any indication
Yes	484 (67%)	602 (66%)	− 0.007 (− 0.14, 0.12)	0.99 (0.81, 1.21)
No	238 (33%)	307 (34%)	− 0.007 (− 0.14, 0.12)	0.99 (0.81, 1.21)
Missing	4	0

IAP intrapartum antibiotic prophylaxis
¹Risk difference; estimates < 0 favour rapid test
²Relative risk; estimates < 1 favour rapid test. Analyses adjusted for cluster size, unit birth rate, and estimated pre-trial IAP rates

ISSN: 1741-7015