From: Intracranial efficacy of alectinib in ALK-positive NSCLC patients with CNS metastases—a multicenter retrospective study
Patients with CNS-related symptoms in the baseline, n = 28
Before the initiation of alectinib
After the treatment of alectinib
ECOG 0-1
9 (32.1%)
21 (75%)
ECOG ≥ 2
19 (67.9%)
7 (25%)