Fig. 3

ROC curve of NT-proBNP for all-cause death risk prediction in 1178 patients with HCM. C-statistics = 0.70 (95% CI 0.67–0.73, P < 0.001); the optimal cut-off value was NT-proBNP > 1780 pg/ml identified by the highest Youden’s index (sensitivity =57.0%, specificity =74.8%). HCM, hypertrophic cardiomyopathy; NT-proBNP, N-terminal pro-brain natriuretic peptide; ROC, receiver operating characteristic