From: Chromosomally normal miscarriage is associated with vaginal dysbiosis and local inflammation
 | Euploid miscarriage | Aneuploid miscarriage | Control (term pregnancy) | p value |
---|---|---|---|---|
Number of women | 54 | 39 | 74 | Â |
Maternal age, years Median (range) | 32 (17–46) | 36 (27–45) | 32 (20–44) | †0.0044 |
BMI (kg/m2) Median (range) | 25.1 (17.7–35) | 24.4 (18.7–39.4) | 24.5 (18–38.4) | †0.205 |
Smokers (%) | 7 (13) | 2 (5.1) | 3 (3.7) | ††0.189 |
Ethnicity (%) | ||||
 White | 30 (56) | 24 (62) | 54 (73) | †††0.1271 |
 Asian | 15 (28) | 11 (28) | 10 (13.5) | |
 Black | 7 (13) | 4 (10) | 10 (13.5) | |
 Mixed | 2 (3) | 0 (0) | 0 (0) | |
Previous miscarriage (%) | ||||
 0 | 30(55.6) | 22 (56.4) | 31 (42) | ††††0.0084 |
 1 | 9(16.7) | 6 (15.3) | 29 (39) | |
 2 | 9 (16.7) | 7 (18) | 10 (14) | |
  ≥ 3 | 6 (11) | 4 (10.3) | 4 (5) | |
Gestational age group at sampling (%) | ||||
 5–8 weeks | 14 (26) | 14 (36) | 7 (10) | †††0.0083 |
 8–10 weeks | 24 (44) | 19 (49) | 41(55) | |
 10–14 weeks | 16 (30) | 6 (15) | 26 (35) | |
Bleeding score | ||||
 0 | 28 | 24 | 65 | †††0.0002 |
 1 | 13 | 11 | 9 | |
 2 | 8 | 2 | 0 | |
 3 | 3 | 2 | 0 | |
 4 | 2 | 0 | 0 | |
Status at sampling | ||||
Missed | 40 | 35 |  | †††0.1 |
Incomplete | 4 | 0 | Â | |
Viable | 10 | 4 | Â |