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Table 1 Clinical and demographic characteristics of 167 patients included in study cohort

From: Chromosomally normal miscarriage is associated with vaginal dysbiosis and local inflammation

  Euploid miscarriage Aneuploid miscarriage Control (term pregnancy) p value
Number of women 54 39 74  
Maternal age, years
Median (range)
32 (17–46) 36 (27–45) 32 (20–44) 0.0044
BMI (kg/m2)
Median (range)
25.1 (17.7–35) 24.4 (18.7–39.4) 24.5 (18–38.4) 0.205
Smokers (%) 7 (13) 2 (5.1) 3 (3.7) ††0.189
Ethnicity (%)
 White 30 (56) 24 (62) 54 (73) †††0.1271
 Asian 15 (28) 11 (28) 10 (13.5)
 Black 7 (13) 4 (10) 10 (13.5)
 Mixed 2 (3) 0 (0) 0 (0)
Previous miscarriage (%)
 0 30(55.6) 22 (56.4) 31 (42) ††††0.0084
 1 9(16.7) 6 (15.3) 29 (39)
 2 9 (16.7) 7 (18) 10 (14)
  ≥ 3 6 (11) 4 (10.3) 4 (5)
Gestational age group at sampling (%)
 5–8 weeks 14 (26) 14 (36) 7 (10) †††0.0083
 8–10 weeks 24 (44) 19 (49) 41(55)
 10–14 weeks 16 (30) 6 (15) 26 (35)
Bleeding score
 0 28 24 65 †††0.0002
 1 13 11 9
 2 8 2 0
 3 3 2 0
 4 2 0 0
Status at sampling
Missed 40 35   †††0.1
Incomplete 4 0  
Viable 10 4  
  1. Kruskal-Wallis test
  2. ††Fisher’s exact (two-tailed)
  3. †††Chi-squared
  4. ††††Chi-squared combining euploid and aneuploid miscarriages and comparing with viable term pregnancies