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Table 2 Cox proportional hazards models for risk of all-cause mortality, cardiovascular mortality, or cardiovascular disease diagnosis by adherence to individual healthy behaviour, stratified by BMI group

From: Obesity, metabolic risk and adherence to healthy lifestyle behaviours: prospective cohort study in the UK Biobank

 

All-cause mortality

Cardiovascular mortality

Incident cardiovascular disease

BMI, kg/m2

18.5–24.9

25–29.9

30–34.9

≥ 35

18.5–24.9

25–29.9

30–34.9

≥ 35

18.5–24.9

25–29.9

30–34.9

≥ 35

Smoking

            

 Never (reference)

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 Previous

1.25 (1.18–1.34)

1.25 (1.19–1.32)

1.27 (1.18–1.37)

1.27 (1.13–1.43)

1.25 (1.09–1.43)

1.25 (1.14–1.38)

1.19 (1.04–1.37)

1.13 (0.92–1.37)

1.12 (1.07–1.18)

1.13 (1.09–1.17)

1.14 (1.08–1.20)

1.16 (1.07–1.26)

 Current

3.07 (2.86–3.30)

2.29 (2.14–2.44)

2.01 (1.80–2.23)

1.85 (1.54–2.22)

3.49 (3.01–4.05)

2.71 (2.40–3.07)

2.29 (1.90–2.75)

1.89 (1.41–2.54)

1.96 (1.84–2.10)

1.69 (1.60–1.78)

1.54 (1.42–1.67)

1.59 (1.39–1.82)

Alcohol (g/week)

            

 None

1.27 (1.08–1.50)

1.00 (0.85–1.17)

1.21 (1.00–1.47)

1.12 (0.87–1.44)

1.52 (1.10–2.11)

1.00 (0.73–1.37)

1.07 (0.72–1.57)

1.06 (0.68–1.65)

1.18 (1.03–1.37)

1.10 (0.98–1.23)

1.37 (1.20–1.57)

1.21 (1.01–1.44)

 Occasional (< 8)

1.32 (1.09–1.61)

1.11 (0.93–1.31)

1.08 (0.85–1.38)

1.22 (0.91–1.62)

1.32 (0.87–2.01)

1.11 (0.78–1.57)

1.14 (0.72–1.79)

1.61 (1.02–2.51)

1.10 (0.93–1.31)

1.10 (0.97–1.25)

1.14 (0.97–1.35)

1.37 (1.12–1.66)

 Moderate (8–112) reference

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 Heavy I (112–168)

0.97 (0.89–1.05)

0.89 (0.83–0.96)

1.08 (0.97–1.20)

1.09 (0.91–1.29)

0.81 (0.67–0.98)

0.88 (0.77–1.01)

1.07 (0.88–1.31)

1.04 (0.77–1.40)

0.94 (0.88–1.01)

0.98 (0.93–1.03)

0.94 (0.87–1.01)

0.96 (0.84–1.09)

 Heavy II (168–224)

0.95 (0.86–1.04)

0.95 (0.88–1.02)

0.88 (0.78–0.99)

1.18 (0.98–1.43)

0.80 (0.65–0.99)

0.87 (0.75–1.01)

0.83 (0.66–1.05)

1.28 (0.94–1.74)

0.94 (0.87–1.02)

0.94 (0.89–1.00)

0.99 (0.91–1.07)

1.10 (0.95–1.25)

 Heavy III (> 224)

1.23 (1.15–1.32)

1.00 (0.95–1.06)

1.12 (1.04–1.22)

1.09 (0.95–1.25)

1.30 (1.13–1.50)

1.05 (0.94–1.16)

1.21 (1.04–1.41)

1.04 (0.82–1.31)

1.05 (0.99–1.12)

0.96 (0.92–1.01)

1.02 (0.96–1.08)

1.04 (0.94–1.15)

Fruit/vegetables (servings/day)

            

 ≥ 5 (reference)

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 < 5

1.17 (1.10–1.25)

1.03 (0.98–1.08)

1.02 (0.94–1.10)

0.98 (0.87–1.10)

1.12 (0.98–1.28)

1.07 (0.97–1.18)

1.02 (0.89–1.17)

1.08 (0.89–1.32)

1.08 (1.03–1.14)

1.05 (1.01–1.09)

1.03 (0.97–1.08)

0.97 (0.89–1.06)

Meeting physical activity guidelines

            

 Yes (reference)

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

 No

1.20 (1.14–1.27)

1.09 (1.04–1.15)

1.13 (1.06–1.21)

1.08 (0.96–1.20)

1.25 (1.11–1.41)

1.06 (0.97–1.16)

1.17 (1.03–1.32)

0.95 (0.79–1.15)

1.07 (1.02–1.13)

1.03 (0.99–1.07)

1.05 (1.00–1.10)

1.05 (0.97–1.14)

  1. Values presented as HR (95% CI); multivariable hazard ratio adjusted for age, sex, ethnicity, Townsend Deprivation Score, education, region, family history of cardiovascular disease, family history of diabetes, and menopausal status