Fig. 4
Estimates of causal effect sizes for genetical predisposition to PCOS on obesity-related traits using all genome-wide significant SNPs. Inverse-variance weighted approach was used as the primary analysis, MR-Egger and weighted median approaches were used as sensitivity analysis. BMI, adult body mass index; PCOS, polycystic ovary syndrome; WHR, waist-to-hip ratio; WHRadjBMI, waist-to-hip ratio adjusted for body mass index; CBMI, childhood body mass index