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Table 4 Incidences of sequelae or persistent symptoms (SPS) after discharge

From: Long COVID 12 months after discharge: persistent symptoms in patients hospitalised due to COVID-19 and patients hospitalised due to other causes—a multicentre cohort study

SPS

Exposed cohort (hospitalised due to COVID-19) (n = 453)

Non-exposed cohort (hospitalised due to other causes) (n = 453)

Risk ratio (95% CI)b

N (Cumulative incidence)a

N (Cumulative incidence)a

Any SPS

120 (26.5)

105 (23.2)

1.14 (0.91 to 1.43)

General/systemic SPS

55 (12.1)

63 (13.9)

0.87 (0.62 to 1.22)

Fatigue

35 (7.7)

40 (8.8)

0.88 (0.57 to 1.35)

Muscle weakness

14 (3.1)

8 (1.8)

1.75 (0.74 to 4.27)

Muscle or joint pain

35 (7.7)

30 (6.6)

1.17 (0.73 to 1.87)

Respiratory SPS

77 (17.0)

58 (12.8)

1.33 (0.97 to 1.82)

Dyspnoea

60 (13.2)

43 (9.5)

1.40 (0.96 to 2.02)

Chest pain

4 (0.9)

6 (1.3)

0.67 (0.19 to 2.37)

Pharyngeal symptoms

16 (3.5)

2 (0.4)

8.00 (1.85 to 36.12)

Neurological SPS

40 (8.8)

25 (5.5)

1.60 (0.99 to 2.59)

Headache

9 (2.0)

9 (2.0)

1.00 (0.40 to 2.50)

Sensitivity disorders

8 (1.8)

7 (1.5)

1.14 (0.42 to 3.12)

Movement disorders

3 (0.7)

1 (0.2)

3.00 (0.30 to 28.70)

Confusion, memory loss

14 (3.1)

4 (0.9)

3.50 (1.16 to 10.55)

Mental health SPS

41 (9.1)

35 (7.7)

1.17 (0.76 to 1.80)

Depressive symptoms

18 (4.0)

16 (3.5)

1.13 (0.58 to 2.18)

Anxiety symptoms

33 (7.3)

14 (3.1)

2.36 (1.28 to 4.34)

Sleep disturbances

10 (2.2)

7 (1.5)

1.43 (0.55 to 3.81)

Haematological SPS

5 (1.1)

4 (0.9)

1.25 (0.34 to 4.62)

Dermatological SPS

8 (1.8)

18 (4.0)

0.46 (0.21 to 1.02)

Nephrological SPS

5 (1.1)

2 (0.4)

2.20 (0.50 to 9.76)

Urological SPS

5 (1.1)

12 (2.6)

0.44 (0.16 to 1.19)

Otorhinolaryngological SPS

4 (0.9)

6 (1.3)

0.69 (0.21 to 2.29)

Ophthalmological SPS

4 (0.9)

14 (3.1)

0.31 (0.11 to 0.89)

Digestive SPS

42 (9.3)

45 (9.9)

0.30 (0.14 to 0.63)

Diarrhoea

35 (7.7)

33 (7.3)

0.93 (0.63 to 1.39)

Constipation

6 (1.3)

9 (2.0)

0.68 (0.25 to 184)

Abdominal pain

12 (2.6)

21 (4.6)

0.58 (0.29 to 1.15)

Infection

7 (1.5)

6 (1.3)

1.15 (0.41 to 3.27)

  1. aCumulative incidence was calculated as new cases of SPS (not present before hospitalisation)/all susceptible patients
  2. bThe non-exposed cohort was used as reference group for risk ratios. Risk ratios show the differences in cumulative incidences (unadjusted) between the exposed and non-exposed cohorts