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Table 3 Taxa regulated by inulin and/or PA in the gut microbiota of mice

From: Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals

  Mean ± SEM Kruskal-Wallis test
LF HF INU Ex INU+ Ex p-value q-value
Phylum
 Firmicutes 51.31 ± 1.3a 53.888 ± 2.866a 41.956 ± 1.555b 51.511 ± 1.468a 40.511 ± 2.228b < 0.001 < 0.001
 Bacteroidetes 37.09 ± 1.357ab 31.25 ± 1.885b 47.9 ± 1.123 ac 35.378 ± 1.05b 49.1 ± 1.553c < 0.001 < 0.001
 Actinobacteria 0.091 ± 0.026a 0.072 ± 0.016a 1.054 ± 0.243b 0.112 ± 0.029a 0.334 ± 0.149ab 0.001 0.002
 Proteobacteria 6.092 ± 0.751ab 8.386 ± 1.38a 4.502 ± 0.688b 8.763 ± 0.902a 6.182 ± 0.571ab 0.005 0.008
Family
 Lachnospiraceae 7.789 ± 0.935a 6.3 ± 0.812ab 5.081 ± 1.016b 6.221 ± 0.614ab 4.497 ± 0.623ab 0.024 0.035
 Ruminococcaceae 27.91 ± 1.44a 28.65 ± 2.351ab 16.678 ± 1.5bc 28.867 ± 1.047a 9.791 ± 0.689c < 0.001 < 0.001
 Coriobacteriaceae 0.087 ± 0.025ab 0.063 ± 0.014ab 0.209 ± 0.071a 0.09 ± 0.025ab 0.056 ± 0.02b 0.017 0.029
 Rikenellaceae 11.562 ± 1.723ab 11.866 ± 1.499ab 8.651 ± 1.26ab 13.822 ± 0.855a 5.727 ± 0.391b 0.002 0.005
 Prevotellaceae 0.673 ± 0.131ab 0.651 ± 0.213ab 1.419 ± 0.348ab 0.39 ± 0.056a 1.492 ± 0.267b 0.003 0.005
 Clostridiales_Incertae_Sedis_XIII 0.089 ± 0.011a 0.079 ± 0.009ab 0.038 ± 0.007ab 0.092 ± 0.017a 0.032 ± 0.005b 0.001 0.003
 Bifidobacteriaceae 0 ± 0a 0 ± 0a 0.842 ± 0.195b 0.015 ± 0.007ab 0.276 ± 0.133b < 0.001 < 0.001
 Peptostreptococcaceae 0.262 ± 0.09a 0.313 ± 0.068a 0.002 ± 0.001b 0.468 ± 0.275a 0.002 ± 0.002b < 0.001 < 0.001
 Desulfovibrionaceae 0.263 ± 0.021a 0.342 ± 0.049ab 0.318 ± 0.075ab 0.594 ± 0.093b 0.168 ± 0.038a 0.002 0.005
Genus
Oscillibacter 8.902 ± 0.597ab 10.54 ± 1.009ab 6.264 ± 0.794bc 10.742 ± 0.524a 2.768 ± 0.334c < 0.001 < 0.001
Clostridium_IV 0.375 ± 0.054a 0.176 ± 0.013ab 0.118 ± 0.032b 0.163 ± 0.022ab 0.086 ± 0.016b < 0.001 < 0.001
Alistipes 11.562 ± 1.723ab 11.853 ± 1.496a 8.634 ± 1.255ab 13.822 ± 0.855a 5.718 ± 0.392b 0.002 0.003
Prevotella 0.173 ± 0.04a 0.042 ± 0.019b 0.106 ± 0.025ab 0.054 ± 0.012ab 0.165 ± 0.028a 0.003 0.005
Parabacteroides 1.869 ± 0.402a 0.113 ± 0.031b 0.143 ± 0.032b 0.343 ± 0.11b 0.895 ± 0.285ab < 0.001 < 0.001
Ruminococcus 0.017 ± 0.006ab 0.013 ± 0.005a 0.071 ± 0.032ab 0.018 ± 0.005ab 0.115 ± 0.044b 0.004 0.006
Bifidobacterium 0 ± 0a 0 ± 0a 0.842 ± 0.195b 0.015 ± 0.007ab 0.276 ± 0.133b < 0.001 < 0.001
Eisenbergiella 0.112 ± 0.052a 0.008 ± 0.002ab 0.001 ± 0b 0.01 ± 0.002ab 0.004 ± 0.002b < 0.001 < 0.001
Clostridium_XlVb 0.049 ± 0.025a 0.006 ± 0.002ab 0 ± 0b 0.063 ± 0.02a 0.001 ± 0.001b < 0.001 < 0.001
Macellibacteroides 0.015 ± 0.003ab 0.002 ± 0.001a 0.002 ± 0.001a 0.005 ± 0.004a 0.048 ± 0.017b < 0.001 < 0.001
Romboutsia 0.262 ± 0.09a 0.313 ± 0.068a 0.002 ± 0.001b 0.468 ± 0.275a 0.002 ± 0.002b < 0.001 < 0.001
Saccharibacteria_genera_incertae_sedis 0.017 ± 0.006 0.011 ± 0.005 0.039 ± 0.011 0.011 ± 0.004 0.041 ± 0.012 0.024 0.031
Bilophila 0.263 ± 0.021a 0.342 ± 0.049ab 0.318 ± 0.075ab 0.594 ± 0.093b 0.168 ± 0.038a 0.002 0.004
  1. The relative abundance of taxa significantly regulated by inulin or voluntary exercise in the cecal content of mice. Results are expressed as mean of relative abundance ± SEM. Significantly affected taxa by inulin or voluntary exercise were identified using a Kruskal-Wallis ANOVA performed in R. p-value was adjusted (q-value, significant if q < 0.05) to control for the false discovery rate (FDR correction) for multiple testing. Ns Not significant. Multiples comparisons were then assessed using Dunn’s post hoc test in R. A different letter was attributed to the groups when the variations between groups are significantly different