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Fig. 5 | BMC Medicine

Fig. 5

From: The association of neurodevelopmental abnormalities, congenital heart and renal defects in a tuberous sclerosis complex patient cohort

Fig. 5

Characterisation of renal involvement in TSC1 and TSC2 patients by abdominal MRI and USS. A The prevalence of angiomyolipoma (AML) and cysts in the kidneys of TSC1 vs TSC2 patients (TSC1, N=21; TSC2, N=65); B The size of AML (mm) as a proportion of total measured tumours (TSC1, N=4; TSC2, N=68); C The prevalence of kidney lesions in either left kidney (L), right kidney (R) or both kidneys (L + R) in TSC1 vs TSC2; L and R compared with Fisher’s exact test (p < 0.05 significance); D The prevalence of kidney lesions as patients age TSC1 vs TSC2 (mean ± SEM); TSC1 vs TSC2 statistically compared with Z-score for 2 population proportions (p < 0.05 significance); MRI, magnetic resonance imaging; USS, ultrasound; * p < 0.05; ** p < 0.01; n.s., non-significant

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BMC Medicine

ISSN: 1741-7015

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