Skip to main content
Fig. 3 | BMC Medicine

Fig. 3

From: Mutations of PI3K-AKT-mTOR pathway as predictors for immune cell infiltration and immunotherapy efficacy in dMMR/MSI-H gastric adenocarcinoma

Fig. 3

Association between NMP and immune cell infiltration in dMMR/MSI-H gastric adenocarcinomas without receiving neoadjuvant chemotherapy. Correlation of NMP with DTICs, including CD3+, CD4+, CD8+, and FOXP3+ cells in central tumor area (left part). Immunohistochemical staining of the representative samples for CD3, CD4, CD8, CD68, and FOXP3 (right part). Scale bar: 5 mm. Every blue point indicates the data of one sample, and the yellow lines are smoothing splines illustrating the trend of association between NMP and DTICs. Abbreviations: DTIC, density of tumor-infiltrating immune cell; dMMR, mismatch repair-deficient; MSI-H, microsatellite instability-high; NMP, number of mutated members of the PI3K-AKT-mTOR pathway

Back to article page

BMC Medicine

ISSN: 1741-7015

Contact us