Fig. 4

Focused panel association analysis of endometrium in cases and controls and different cycle phases. A Populations with significantly different relative abundance between proliferative and secretory phases in control and endometriosis patients and showing contrary fluctuation between both groups (median relative abundance is shown). p-values: dashed lines, p ≤ 0.0005; dotted lines, p ≤ 0.00005. B Significant differences in abundance of immune populations between control and endometriosis patients. p-values: *, p ≤ 0.05; **, p ≤ 0.005; ***, p ≤ 0.0005; **** p ≤ 0.00005. C Significant differences in marker expression in immune populations between control and endometriosis patients (p ≤ 0.1). n = 13 controls (9 PE and 4 SE) and n = 18 endometriosis (13 PE (8 mild and 5 severe stages) and 5 SE (all mild stage of disease)). Green: controls; red: cases. All analyses were performed in both phases of the menstrual cycle. PE: proliferative, SE: secretory