Fig. 1

Cumulative hazard of incident coronary heart disease (CHD) for each category of TV viewing, computer use and genetic risk across age ranges. Cox regression models using age as the underlying timescale were adjusted for sex, body mass index (weight in kilograms/height in meters squared), smoking status (never, previous, current), employment (unemployed, employed), Townsend Deprivation Index (a numerical deprivation score generated based on employment, car ownership, home ownership and household overcrowding according to postcode of participants’ home address), alcohol consumption (never, previous, currently <3 times/week, currently ≥3 times/week), salt-adding behaviour (never/rarely, sometimes, usually, always), oily fish consumption (never, <once/week, once/week, >once/week), coffee intake (cups/day), fruit and vegetable intake (a composite score generated based on intake of fresh/dried fruit and intake of raw/cooked vegetable ranging from 0 to 4), processed/red meat intake (days/week), hypertension medication use, cholesterol-lowering medication use, glucose-lowering medication use, sleep (≤5, 6, 7, 8 and ≥9h/day), moderate-to-vigorous physical activity (minutes/day), polygenic risk scores, genotype array type and first ten principal components of genetic ancestry, with mutual adjustment of TV viewing and computer use in models using either TV viewing or computer use as the main exposure; and adjusted for sex, the genotype array type and first ten principal components of genetic ancestry in models using polygenic risk scores as the main exposure