| Event/total (%) | Unadjusted models | Adjusted models | ||||
---|---|---|---|---|---|---|---|
1–2 SMuRFs vs no SMuRFs | 3–4 SMuRFs vs no SMuRFs | Pinteraction | 1–2 SMuRFs vs no SMuRFs | 3–4 SMuRFs vs no SMuRFs | Pinteraction | ||
Age | Â | Â | Â | 0.27 | Â | Â | 0.20 |
 <55 | 129/4834 (2.7) | 0.85 (0.49–1.49) | 0.67 (0.34–1.32) |  | 1.76 (0.81–3.81) | 1.79 (0.73–4.39) |  |
 55–<75 | 597/8659 (6.9) | 0.95 (0.74–1.22) | 0.86 (0.63–1.16) |  | 1.38 (1.03–1.87) | 1.38 (0.96–1.99) |  |
 ≥75 | 466/2614 (17.8) | 0.77 (0.62–0.97) | 0.97 (0.70–1.35) |  | 0.90 (0.69–1.18) | 1.27 (0.85–1.89) |  |
Sex | Â | Â | Â | 0.07 | Â | Â | 0.88 |
 Male | 708/12381 (5.7) | 0.76 (0.61–0.94) | 0.59 (0.45–0.77) |  | 1.13 (0.87–1.47) | 1.25 (0.89–1.75) |  |
 Female | 500/3847 (13.0) | 0.86 (0.68–1.09) | 0.93 (0.68–1.27) |  | 1.18 (0.90–1.56) | 1.46 (1.01–2.11) |  |
Hospital class | Â | Â | Â | 0.65 | Â | Â | 0.96 |
 Province-level | 251/5256 (4.8) | 1.01 (0.66–1.55) | 0.87 (0.53–1.43) |  | 1.13 (0.70–1.82) | 1.19 (0.67–2.10) |  |
 Prefecture-level | 670/8808 (7.6) | 0.76 (0.61–0.94) | 0.64 (0.48–0.84) |  | 1.13 (0.88–1.45) | 1.32 (0.95–1.85) |  |
 County-level | 287/2164 (13.3) | 0.73 (0.54–0.99) | 0.75 (0.50–1.12) |  | 1.38 (0.93–2.03) | 1.69 (1.01–2.83) |  |
Time from onset | Â | Â | Â | 0.055 | Â | Â | 0.01 |
 <12 h | 694/10818 (6.4) | 0.69 (0.56–0.85) | 0.52 (0.40–0.69) |  | 0.99 (0.77–1.27) | 0.97 (0.70–1.35) |  |
 ≥12 h | 503/5284 (9.5) | 0.85 (0.66–1.09) | 0.87 (0.63–1.20) |  | 1.39 (1.03–1.87) | 2.06 (1.41–3.01) |  |
Primary PCI | Â | Â | Â | 0.89 | Â | Â | 0.39 |
 Yes | 248/7017 (3.5) | 0.77 (0.53–1.13) | 0.75 (0.48–1.17) |  | 0.85 (0.55–1.30) | 0.95 (0.57–1.59) |  |
 No | 952/9069 (10.5) | 0.78 (0.65–0.92) | 0.69 (0.54–0.87) |  | 1.24 (1.00–1.53) | 1.41 (1.06–1.87) |  |
Killip class | Â | Â | Â | 0.07 | Â | Â | 0.10 |
 I–II | 866/14976 (5.8) | 0.69 (0.58–0.83) | 0.56 (0.44–0.72) |  | 1.09 (0.88–1.34) | 1.37 (1.02–1.83) |  |
 III–IV | 332/1181(28.1) | 1.07 (0.77–1.50) | 0.88 (0.59–1.32) |  | 1.47 (0.95–2.28) | 1.51 (0.91–2.52) |  |
LVEF<40% | Â | Â | Â | 0.29 | Â | Â | 0.49 |
 No | 362/11683 (3.1) | 0.83 (0.61–1.14) | 0.62 (0.41–0.92) |  | 1.06 (0.76–1.49) | 1.01 (0.64–1.60) |  |
 Yes | 126/929 (13.6) | 1.08 (0.62–1.87) | 1.11 (0.58–2.10) |  | 1.32 (0.70–2.46) | 1.23 (0.56–2.68) |  |
GRACE score | Â | Â | Â | 0.88 | Â | Â | 0.89 |
 ≤140 | 124/6933 (1.8) | 0.83 (0.46–1.49) | 0.81 (0.41–1.58) |  | 0.95 (0.50–1.79) | 1.13 (0.54–2.38) |  |
 >140 | 949/8500 (11.2) | 0.94 (0.78–1.14) | 0.97 (0.77–1.23) |  | 1.15 (0.94–1.40) | 1.30 (0.99–1.69) |  |