Table 2 Distribution of phenotypes of cytochromes enzymes involved in the metabolism of citalopram, paroxetine, fluoxetine, and sertraline among the participants
Total | Citalopram | Fluoxetine | Paroxetine | Sertraline | |
|---|---|---|---|---|---|
N = 663 | N = 202 | N = 191 | N = 107 | N = 163 | |
CYP2C19 | |||||
Poor/intermediate metabolizer, n | 196 (30%) | 58 (29%) | 46 (28%) | ||
Normal metabolizer, n | 268 (40%) | 83 (41%) | 66 (41%) | ||
Rapid/ultrarapid metabolizer, n | 199 (30%) | 61 (30%) | 51 (31%) | ||
CYP2D6 | |||||
Poor/intermediate metabolizer, n | 462 (70%) | 136 (71%) | 70 (65%) | 127 (78%) | |
Normal metabolizer, n | 191 (29%) | 53 (28.9%) | 34 (32%) | 31 (19%) | |
Rapid/ultrarapid metabolizer, n | 10 (1%) | 2 (0.1%) | 3 (3%) | 5 (3%) | |
CYP2C9 | |||||
Poor/intermediate metabolizer, n | 234 (35%) | 70 (37%) | |||
Normal metabolizer, n | 429 (65%) | 121 (63%) | |||