Table 3 Sensitivity analysis regarding the risk of IBS according to Quartiles of baseline fatty liver index

Sensitivity analysis 1: excluding IBS participants diagnosed within 1 year after baseline (N = 396,184)

 Quartile 1

1691

98,180

Reference

 < 0.001

 Quartile 2

1659

99,151

1.15 (1.08–1.24)

 < 0.001

 Quartile 3

1552

99,565

1.19 (1.11–1.28)

 < 0.001

 Quartile 4

1573

99,288

1.21 (1.12–1.31)

 < 0.001

Sensitivity analysis 2: excluding IBS participants diagnosed within 2 years after baseline (N = 395,546)

 Quartile 1

1509

97,998

Reference

 Quartile 2

1495

98,987

1.16 (1.08–1.25)

 < 0.001

 < 0.001

 Quartile 3

1405

99,418

1.20 (1.11–1.30)

 < 0.001

 Quartile 4

1428

99,143

1.22 (1.13–1.32)

 < 0.001

Sensitivity analysis 3: excluding incident alcoholic liver disease participants after baseline (N = 395,775)

 Quartile 1

1878

98,306

Reference

 Quartile 2

1793

99,161

1.12 (1.05–1.20)

0.001

 < 0.001

 Quartile 3

1696

99,496

1.18 (1.10–1.26)

 < 0.001

 Quartile 4

1737

98,812

1.21 (1.13–1.30)

 < 0.001

Sensitivity analysis 4: competing risk model (N = 396,838, No. of competing events = 24,742)

 Quartile 1

1882

98,371

Reference

 Quartile 2

1797

99,289

1.13 (1.05–1.20)

0.001

 < 0.001

 Quartile 3

1701

99,714

1.18 (1.10–1.26)

 < 0.001

 Quartile 4

1749

99,464

1.21 (1.12–1.30)

 < 0.001

Sensitivity analysis 5: excluding HBV or HCV antigen-positive participants after baseline (N = 396,613)

 Quartile 1

1877

98,310

Reference

 Quartile 2

1796

99,235

1.13 (1.05, 1.20)

 < 0.001

 < 0.001

 Quartile 3

1701

99,665

1.18 (1.10, 1.26)

 < 0.001

 Quartile 4

1749

99,403

1.21 (1.13, 1.30)

 < 0.001

Sensitivity analysis 6: additionally adjusted psychologic disorder including depression and anxiety (N = 396,838)

 Quartile 1

1882

98,371

Reference

 Quartile 2

1797

99,289

1.11 (1.03–1.18)

0.003

 < 0.001

 Quartile 3

1701

99,714

1.14 (1.07–1.23)

 < 0.001

 Quartile 4

1749

99,464

1.16 (1.08–1.24)

 < 0.001