From: Modified cardiovascular SOFA score in sepsis: development and internal and external validation
 | Original model | Modified model | Vasopressor only model | pa | pb |
---|---|---|---|---|---|
AUROC (95% CI) of cardiovascular SOFA | |||||
 Derivation cohort | 0.624 (0.596–0.652) | 0.682 (0.654–0.709) | 0.625 (0.597–0.653) |  < 0.001 | 0.125 |
 Internal validation | 0.638 (0.596–0.680) | 0.716 (0.678–0.754) | 0.640 (0.598–0.683) |  < 0.001 | 0.023 |
 External validation 1 | 0.557 (0.536–0.579) | 0.648 (0.627–0.669) | 0.610 (0.587–0.632) |  < 0.001 |  < 0.001 |
 External validation 2 | 0.589 (0.565–0.612) | 0.674 (0.650–0.700) | 0.635 (0.610–0.660) |  < 0.001 |  < 0.001 |
AUROC (95% CI) of total SOFA | |||||
 Derivation cohort | 0.750 (0.725–0.776) | 0.762 (0.738–0.787) | 0.751 (0.725–0.776) |  < 0.001 | 0.682 |
 Internal validation | 0.773 (0.736–0.810) | 0.787 (0.751–0.822) | 0.774 (0.738–0.811) | 0.001 | 0.495 |
 External validation 1 | 0.678 (0.658–0.699) | 0.712 (0.693–0.732) | 0.704 (0.684–0.724) |  < 0.001 |  < 0.001 |
 External validation 2 | 0.712 (0.688–0.735) | 0.736 (0.714–0.758) | 0.726 (0.703–0.749) |  < 0.001 |  < 0.001 |