Table 3 Area under the receiver operating characteristic for predicting 28-day mortality in the original, modified, and vasopressor only cardiovascular/total SOFA

AUROC (95% CI) of cardiovascular SOFA

 Derivation cohort

0.624

(0.596–0.652)

0.682

(0.654–0.709)

0.625

(0.597–0.653)

 < 0.001

 Internal validation

0.638

(0.596–0.680)

0.716

(0.678–0.754)

0.640

(0.598–0.683)

 < 0.001

 External validation 1

0.557

(0.536–0.579)

0.648

(0.627–0.669)

0.610

(0.587–0.632)

 < 0.001

 External validation 2

0.589

(0.565–0.612)

0.674

(0.650–0.700)

0.635

(0.610–0.660)

 < 0.001

AUROC (95% CI) of total SOFA

 Derivation cohort

0.750

(0.725–0.776)

0.762

(0.738–0.787)

0.751

(0.725–0.776)

 < 0.001

 Internal validation

0.773

(0.736–0.810)

0.787

(0.751–0.822)

0.774

(0.738–0.811)

0.001

 External validation 1

0.678

(0.658–0.699)

0.712

(0.693–0.732)

0.704

(0.684–0.724)

 < 0.001

 External validation 2

0.712

(0.688–0.735)

0.736

(0.714–0.758)

0.726

(0.703–0.749)

 < 0.001