Skip to main content

Table 1 Characteristics of the study population and the median age of the diagnosis of the first two diseases

From: Sex-specific patterns and lifetime risk of multimorbidity in the general population: a 23-year prospective cohort study

  All participants
(n = 6094)
Men
(n = 2585, 42.4%)
Women
(n = 3509, 57.6%)
p-value for sex differences1
Age (years), median (IQR) 60.8 (57.1–66.7) 60.4 (56.7–65.9) 61.1 (57.3–67.5) < 0.001
Years of follow-up, median (IQR) 9.2 (7.1–13.4) 9.3 (7.2–12.7) 9.1 (7.0–13.8) 0.58
Marital status < 0.001
 Living with partner 4619 (80.3%) 2244 (90.4%) 2375 (72.8%)  
 Living without partner 1127 (19.6%) 239 (9.6%) 888 (27%)  
Education < 0.001
 Primary 636 (10.4%) 210 (8%) 426 (14%)  
 Lower secondary 2462 (40.5%) 703 (30%) 1759 (55%)  
 Further secondary 1189 (19.5%) 724 (38%) 465 (24%)  
 Higher 1782 (29.3%) 938 (23%) 844 (7%)  
Smoking status < 0.001
 Never 1945 (32.2%) 461 (17.8%) 1484 (42.9%)  
 Former 2690 (44.5%) 1396 (53.2%) 1294 (37.4%)  
 Current 1410 (23.0%) 719 (27.9%) 682 (19.7%)  
Blood pressure (mm Hg), median (IQR)  
 Systolic 135 (122–148) 136 (124–149) 134 (120–148) < 0.001
 Diastolic 79 (72–86) 80 (73–87) 78 (71–86) < 0.001
Ancestry 0.8
 European 5378 (97.9%) 2280 (98.0%) 3098 (97.9%)  
 East-Asian 63 (1.1%) 28 (1.2%) 35 (1.1%)  
 African 37 (0.7%) 13 (0.6%) 24 (0.8%)  
 Admixed 13 (0.2%) 5 (0.2%) 8 (0.3%)  
Age at diagnosis (years), median (IQR)2  
 First disease 71.9 (64.5–79.0) 71.0 (64.0–77.6) 72.9 (64.9–80.3) < 0.001
 Second disease 78.1 (71.8–84.0) 77.0 (71.1–82.7) 79.0 (72.6–84.9) < 0.001
  1. Key sex differences in the population characteristics are highlighted in bold
  2. IQR interquartile range
  3. Data at baseline were near complete (<3% missing), with the exception of the ancestry characteristic which had 9.8% of missing data (missing data were excluded when calculating the proportions)
  4. 1p-values were calculated using Wilcoxon-Mann-Whitney rank sum for continuous variables (with the null hypothesis of equal medians) and chi-squared test for categorical variables
  5. 2The values were calculated excluding participants who were censored or died without any diagnosis (for the age at the diagnosis of the first disease) or who were censored or died with only one diagnosis (for the age at the diagnosis of the second disease)