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Table 3 HRs (95% CIs) for mortality according to serum 25(OH)D concentrations among participants with OA

From: L-shaped association of serum 25-hydroxyvitamin D concentrations with cardiovascular and all-cause mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study

  Serum 25(OH)D concentrations (nmol/L) P trend
< 25.00 25.00–49.99 50.00–74.99 ≥ 75.00
All-cause mortality
 Number of deaths (%) 24 (24.00) 126 (21.39) 173 (18.12) 115 (12.61)  
 Model 1
HR (95% CI) P-value
1.00 0.78 (0.50, 1.20) 0.25 0.65 (0.42, 0.99) <0.05 0.59 (0.38, 0.92) 0.02 <0.01
 Model 2
HR (95% CI) P-value
1.00 0.59 (0.38, 0.92) 0.02 0.42 (0.27, 0.66) <0.01 0.38 (0.24, 0.60) <0.01 <0.01
 Model 3
HR (95% CI) P-value
1.00 0.53 (0.29, 0.96) 0.04 0.43 (0.24, 0.77) <0.01 0.44 (0.24, 0.81) <0.01 0.02
CVD mortality
 Number of deaths (%) 4 (4.00) 20 (3.40) 31 (3.25) 19 (2.08)  
 Model 1
HR (95% CI) P-value
1.00 0.76 (0.26, 2.23) 0.62 0.73 (0.26, 2.06) 0.55 0.57 (0.19, 1.66) 0.30 0.09
 Model 2
HR (95% CI) P-value
1.00 0.62 (0.21, 1.87) 0.40 0.47 (0.16, 1.40) 0.18 0.37 (0.12, 1.15) 0.08 0.57
 Model 3
HR (95% CI) P-value
1.00 0.16 (0.04, 0.60) <0.01 0.19 (0.05, 0.68) 0.01 0.18 (0.05, 0.68) 0.01 0.41
Cancer mortality
 Number of deaths (%) 3 (3.00) 20 (3.40) 34 (3.56) 21 (2.30)  
 Model 1
HR (95% CI) P-value
1.00 0.98 (0.29, 3.31) 0.98 1.00 (0.31, 3.26) 1.00 0.86 (0.26, 2.89) 0.81 0.24
 Model 2
HR (95% CI) P-value
1.00 0.85 (0.25, 2.91) 0.80 0.81 (0.24, 2.73) 0.73 0.64 (0.18, 2.26) 0.49 0.10
 Model 3
HR (95% CI) P-value
1.00 0.65 (0.17, 2.41) 0.52 0.63 (0.17, 2.35) 0.49 0.47 (0.12, 1.87) 0.28 0.40
  1. Model 1: Non-adjusted
  2. Model 2: Adjusted for age, sex, race/ethnicity, survey cycle
  3. Model 3: Adjusted for age, sex, race/ethnicity, survey cycle, education level, PIR, BMI, smoking status, alcohol consumption, disease duration of OA, and history of hypertension or diabetes