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Table 3 HRs (95% CIs) for mortality according to serum 25(OH)D concentrations among participants with OA

From: L-shaped association of serum 25-hydroxyvitamin D concentrations with cardiovascular and all-cause mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study

 

Serum 25(OH)D concentrations (nmol/L)

P trend

< 25.00

25.00–49.99

50.00–74.99

≥ 75.00

All-cause mortality

 Number of deaths (%)

24 (24.00)

126 (21.39)

173 (18.12)

115 (12.61)

 

 Model 1

HR (95% CI) P-value

1.00

0.78 (0.50, 1.20) 0.25

0.65 (0.42, 0.99) <0.05

0.59 (0.38, 0.92) 0.02

<0.01

 Model 2

HR (95% CI) P-value

1.00

0.59 (0.38, 0.92) 0.02

0.42 (0.27, 0.66) <0.01

0.38 (0.24, 0.60) <0.01

<0.01

 Model 3

HR (95% CI) P-value

1.00

0.53 (0.29, 0.96) 0.04

0.43 (0.24, 0.77) <0.01

0.44 (0.24, 0.81) <0.01

0.02

CVD mortality

 Number of deaths (%)

4 (4.00)

20 (3.40)

31 (3.25)

19 (2.08)

 

 Model 1

HR (95% CI) P-value

1.00

0.76 (0.26, 2.23) 0.62

0.73 (0.26, 2.06) 0.55

0.57 (0.19, 1.66) 0.30

0.09

 Model 2

HR (95% CI) P-value

1.00

0.62 (0.21, 1.87) 0.40

0.47 (0.16, 1.40) 0.18

0.37 (0.12, 1.15) 0.08

0.57

 Model 3

HR (95% CI) P-value

1.00

0.16 (0.04, 0.60) <0.01

0.19 (0.05, 0.68) 0.01

0.18 (0.05, 0.68) 0.01

0.41

Cancer mortality

 Number of deaths (%)

3 (3.00)

20 (3.40)

34 (3.56)

21 (2.30)

 

 Model 1

HR (95% CI) P-value

1.00

0.98 (0.29, 3.31) 0.98

1.00 (0.31, 3.26) 1.00

0.86 (0.26, 2.89) 0.81

0.24

 Model 2

HR (95% CI) P-value

1.00

0.85 (0.25, 2.91) 0.80

0.81 (0.24, 2.73) 0.73

0.64 (0.18, 2.26) 0.49

0.10

 Model 3

HR (95% CI) P-value

1.00

0.65 (0.17, 2.41) 0.52

0.63 (0.17, 2.35) 0.49

0.47 (0.12, 1.87) 0.28

0.40

  1. Model 1: Non-adjusted
  2. Model 2: Adjusted for age, sex, race/ethnicity, survey cycle
  3. Model 3: Adjusted for age, sex, race/ethnicity, survey cycle, education level, PIR, BMI, smoking status, alcohol consumption, disease duration of OA, and history of hypertension or diabetes