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Fig. 4 | BMC Medicine

Fig. 4

From: Changes in concentrations of cervicovaginal immune mediators across the menstrual cycle: a systematic review and meta-analysis of individual patient data

Fig. 4

Validation and exploratory experiments. A Concentrations of validation cytokines. Each symbol shows the concentration in a single sample. Lines connect samples from the same participant. Pale grey symbols are below the lower limit of detection. B Differences in concentrations between phases of the menstrual cycle for the validation cytokines. Black shows the new data generated in this study, gray shows all other studies. Error bars for several CCL2 and IL-1α studies extend off-scale. Black-filled symbols indicate p<0.05, open symbols indicate p>0.05. C Concentrations of exploratory cytokines, as in A. D Differences in concentrations between phases of the menstrual cycle for the exploratory cytokines, as in B. Error bars for several IgA and IgM studies extend off-scale

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