Skip to main content

Table 1 Overall SARS-CoV-2 seroprevalence (values for seronegativity are not included) by isotype and isotype-antigen combination in the study participants by vaccination status (n = 1.076)

From: SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia

  Fully vaccinated Partially vaccinated Non-vaccinated
  Positive Undetermined Positive Undetermined Positive Undetermined
  n (%) n (%) n (%) n (%) n (%) n (%)
Overall 674 (99.3) 3 (0.4) 252 (94.4) 5 (1.9) 70 (53.8) 13 (10.0)
By isotype
 IgM 160 (23.6) 88 (13.0) 46 (17.2) 26 (9.7) 17 (13.1) 13 (10.0)
 IgA 509 (75.0) 56 (8.2) 148 (55.4) 29 (10.9) 54 (41.5) 11 (8.5)
 IgG 673 (99.1) 3 (0.4) 240 (89.9) 7 (2.6) 59 (45.4) 8 (6.2)
By antigen
 N 33 (4.9) 66 (9.7) 28 (10.5) 20 (7.5) 18 (13.8) 18 (13.8)
  NFL 21 (3.1) 59 (8.7) 16 (6.0) 27 (10.1) 15 (11.5) 17 (13.1)
  NCt 13 (1.9) 26 (3.8) 14 (5.2) 6 (2.2) 6 (4.6) 3 (2.3)
 RBD 670 (98.7) 5 (0.7) 231 (86.5) 12 (4.5) 60 (46.2) 7 (5.4)
 S 655 (96.5) 19 (2.8) 208 (77.9) 40 (15.0) 58 (44.6) 11 (8.5)
 S2 449 (66.1) 171 (25.2) 111 (41.6) 70 (26.2) 47 (36.2) 18 (13.8)
By isotype-antigen combination
 IgM NFL 0 (0.0) 5 (0.7) 1 (0.4) 8 (3.0) 0 (0.0) 3 (2.3)
 IgM NCt 2 (0.3) 10 (1.5) 5 (1.9) 1 (0.4) 0 (0.0) 1 (0.8)
 IgM RBD 60 (8.8) 87 (12.8) 19 (7.1) 27 (10.1) 11 (8.5) 10 (7.7)
 IgM S 87 (12.8) 137 (20.2) 15 (5.6) 37 (13.9) 5 (3.8) 11 (8.5)
 IgM S2 1 (0.1) 18 (2.7) 0 (0.0) 7 (2.6) 1 (0.8) 2 (1.5)
 IgA NFL 14 (2.1) 27 (4.0) 9 (3.4) 18 (6.7) 2 (1.5) 12 (9.2)
 IgA NCt 9 (1.3) 17 (2.5) 8 (3.0) 7 (2.6) 5 (3.8) 2 (1.5)
 IgA RBD 382 (56.3) 64 (9.4) 82 (30.7) 13 (4.9) 30 (23.1) 9 (6.9)
 IgA S 490 (72.2) 57 (8.4) 129 (48.3) 21 (7.9) 40 (30.8) 16 (12.3)
 IgA S2 175 (25.8) 217 (32.0) 52 (19.5) 68 (25.5) 19 (14.6) 29 (22.3)
 IgG NFL 4 (0.6) 42 (6.2) 2 (0.7) 13 (4.9) 11 (8.5) 12 (9.2)
 IgG NCt 0 (0.0) 3 (0.4) 0 (0.0) 0 (0.0) 0 (0.0) 2 (1.5)
 IgG RBD 668 (98.4) 6 (0.9) 224 (83.9) 13 (4.9) 58 (44.6) 4 (3.1)
 IgG S 647 (95.3) 26 (3.8) 175 (65.5) 64 (24.0) 40 (30.8) 21 (16.2)
 IgG S2 344 (50.7) 264 (38.9) 52 (19.5) 103 (38.6) 30 (23.1) 27 (20.8)
  1. All p-values <0.05 except for IgM RBD, IgM S2, IgA NFL, IgA NCt, and IgG NCt