Table 2 Triangular motifs for depression severity and taxonomic and functional abundances. Listed are all triangular motifs within the joint network, formed by taxonomic-metabolic, taxonomic-psychopathological and metabolic-psychopathological associations. Related associations are alternately highlighted in grey or white

 Bacteroidetes: Odoribacter

Carbohydrate metabolism: pectin degradation^a

2.026

0.455

 Bacteroidetes: Odoribacter

Depression: HADS

1.956

− 0.457

 Carbohydrate metabolism: pectin degradation^a

Depression: HADS

0.804

− 0.343

 Bacteroidetes: Odoribacter

Carbohydrate metabolism: PRPP biosynthesis^b

1.291

− 0.390

 Bacteroidetes: Odoribacter

Depression: HADS

1.956

− 0.457

 Carbohydrate metabolism: PRPP biosynthesis^b

Depression: HADS

0.655

0.324

 Bacteroidetes: Odoribacter

Glycan metabolism: dermatan sulfate degradation^c

2.611

0.498

 Bacteroidetes: Odoribacter

Depression: HADS

1.956

− 0.457

 Glycan metabolism: dermatan sulfate degradation^c

Depression: HADS

0.530

− 0.307

 Bacteroidetes: Alistipes

Glycan metabolism: dermatan sulfate degradation^c

1.644

0.423

 Bacteroidetes: Alistipes

Depression: HADS

0.997

− 0.365

 Glycan metabolism: dermatan sulfate degradation^c

Depression: HADS

0.530

− 0.307

 Firmicutes: Anaerotruncus

Glycan metabolism: dermatan sulfate degradation^c

1.098

0.370

 Firmicutes: Anaerotruncus

Depression: HADS

0.530

− 0.307

 Glycan metabolism: dermatan sulfate degradation^c

Depression: HADS

0.666

− 0.326

 Firmicutes: Intestinimonas

Amino acid metabolism: methionine biosynthesis^d

0.509

− 0.300

 Firmicutes: Intestinimonas

Fatigue: WEIMuS

0.972

− 0.363

 Amino acid metabolism: methionine biosynthesis^d

Fatigue: WEIMuS

0.959

0.361

 Firmicutes: Eubacterium

Carbohydrate metabolism: pentose phosphate pathway^e

1.082

− 0.369

 Firmicutes: Eubacterium

Fatigue: WEIMuS

0.655

− 0.324

 Carbohydrate metabolism: pentose phosphate pathway^e

Fatigue: WEIMuS

0.715

0.332

 Firmicutes: Anaerotruncus

Carbohydrate metabolism: pentose phosphate pathway^e

0.554

− 0.306

 Firmicutes: Anaerotruncus

Fatigue: WEIMuS

0.662

− 0.325

 Carbohydrate metabolism: pentose phosphate pathway^e

Fatigue: WEIMuS

0.715

0.332

 Firmicutes: Clostridiales genus incertae sedis

Carbohydrate metabolism: pentose phosphate pathway^e

2.900

− 0.517

 Firmicutes: Clostridiales genus incertae sedis

Fatigue: WEIMuS

0.660

− 0.325

 Carbohydrate metabolism: pentose phosphate pathway^e

Fatigue: WEIMuS

0.715

0.332