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Table 2 Main characteristics of the control (Ctrl) and case (Case) sub-populations in the eight cancer type-specific EPIC studies

From: Pan-cancer analysis of pre-diagnostic blood metabolite concentrations in the European Prospective Investigation into Cancer and Nutrition

 

BrC study

CRC study

EnC study

KiC study

GBTC study

HCC study

Adv. PrC study

Loc. PrC study

N = 1088 pairs

N = 1500 pairs

N = 689 pairs

N = 511 pairs

N = 85 pairs

N = 121 pairs

N = 533 pairs

N = 1301 pairs

Ctrl

Case

Ctrl

Case

Ctrl

Case

Ctrl

Case

Ctrl

Case

Ctrl

Case

Ctrl

Case

Ctrl

Case

Age at blood collection

 Mean (SD)

51.8 (8.31)

51.8 (8.33)

57.0 (7.58)

57.1 (7.57)

54.3 (7.83)

54.3 (7.84)

55.8 (8.47)

55.8 (8.46)

58.7 (7.13)

58.7 (7.08)

59.9 (7.01)

59.9 (6.98)

57.6 (7.18)

57.6 (7.18)

57.9 (6.80)

58.0 (6.80)

Age at cancer diagnosis

 Mean (SD)

- -

60.4 (8.83)

- -

64.9 (8.18)

--

62.7 (8.16)

- -

64.5 (8.83)

- -

64.9 (7.60)

- -

66.1 (7.49)

--

66.3 (7.02)

--

67.1 (6.36)

Sex

 Female

1088 (100%)

1088 (100%)

769 (51.3%)

769 (51.3%)

689 (100%)

689 (100%)

197 (38.6%)

197 (38.6%)

48 (56.5%)

48 (56.5%)

35 (28.9%)

35 (28.9%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

BMI (kg/m2)

 Mean (SD)

25.7 (4.32)

26.2 (4.80)

26.5 (3.88)

27.2 (4.34)

26.0 (4.29)

28.2 (5.52)

26.7 (3.84)

27.8 (4.47)

26.9 (4.38)

27.3 (3.98)

26.9 (3.72)

28.4 (4.73)

26.7 (3.48)

27.0 (3.20)

27.5 (3.49)

27.2 (3.37)

Education

 None

56 (5.1%)

62 (5.7%)

124 (8.3%)

136 (9.1%)

67 (9.7%)

76 (11.0%)

42 (8.2%)

34 (6.7%)

6 (7.1%)

6 (7.1%)

6 (5.0%)

7 (5.8%)

28 (5.3%)

32 (6.0%)

106 (8.1%)

136 (10.5%)

 Primary school completed

397 (36.5%)

377 (34.7%)

574 (38.3%)

526 (35.1%)

269 (39.0%)

231 (33.5%)

184 (36.0%)

186 (36.4%)

33 (38.8%)

39 (45.9%)

49 (40.5%)

52 (43.0%)

160 (30.0%)

166 (31.1%)

444 (34.1%)

411 (31.6%)

 Technical/professional school

245 (22.5%)

254 (23.3%)

333 (22.2%)

334 (22.3%)

124 (18.0%)

118 (17.1%)

107 (20.9%)

109 (21.3%)

20 (23.5%)

15 (17.6%)

31 (25.6%)

38 (31.4%)

140 (26.3%)

127 (23.8%)

305 (23.4%)

306 (23.5%)

 Secondary school

158 (14.5%)

178 (16.4%)

188 (12.5%)

227 (15.1%)

100 (14.5%)

127 (18.4%)

66 (12.9%)

72 (14.1%)

11 (12.9%)

8 (9.4%)

11 (9.1%)

5 (4.1%)

58 (10.9%)

59 (11.1%)

103 (7.9%)

91 (7.0%)

 Longer education (incl. University deg.)

211 (19.4%)

195 (17.9%)

241 (16.1%)

227 (15.1%)

100 (14.5%)

100 (14.5%)

96 (18.8%)

93 (18.2%)

15 (17.6%)

17 (20.0%)

22 (18.2%)

17 (14.0%)

132 (24.8%)

124 (23.3%)

306 (23.5%)

324 (24.9%)

 Not specified

21 (1.9%)

22 (2.0%)

40 (2.7%)

50 (3.3%)

29 (4.2%)

37 (5.4%)

16 (3.1%)

17 (3.3%)

0 (0%)

0 (0%)

2 (1.7%)

2 (1.7%)

15 (2.8%)

25 (4.7%)

37 (2.8%)

33 (2.5%)