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Fig. 4 | BMC Medicine

Fig. 4

From: Immunogenicity, efficacy, and safety of SARS-CoV-2 vaccine dose fractionation: a systematic review and meta-analysis

Fig. 4

Comparison of T cell responses against the ancestral strains elicited by dose fractioning of COVID-19 vaccines. The size of dots represents the total sample sizes of the standard and non-standard dose groups. A Compared to pre-vaccination. If the mean and 95% CI of the difference in mean T cell levels before and after the fractional doses were all greater than 0, we determined T cell responses were significantly higher between the groups. B Compared to people who received standard doses. If the mean and 95% CI of the difference in mean T cell levels between the fractional and standard dose groups were all greater or less than 0, we determined T cell responses were significantly higher or lower than that elicited by the standard dose

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