Table 1 Baseline characteristics of included melanoma patients
Characteristic | Total (N = 42) |
|---|---|
Median age, years (range) | 56.0 (31.0, 69.0) |
Gender, N (%) | |
Female | 20 (47.6) |
Male | 22 (52.4) |
Median BMI, kg/m2 (range) | 24.2 (18.4, 36.0) |
ECOG performance status, N (%) | |
0 | 15 (35.7) |
1 | 27 (64.3) |
Pathological type, N (%) | |
Acral melanoma | 23 (54.8) |
Mucosal melanoma | 13 (31.0) |
Other types of melanoma | 6 (14.3) |
TNM stage, N (%) | |
III | 5 (11.9) |
IV | 37 (88.1) |
Mutant of NRAS, N (%) | |
Q61R | 21 (50.0) |
Q61K | 7 (16.7) |
Q61L | 3 (7.1) |
Q61H | 1 (2.4) |
G12D/G12R/G12S/G13C/G60E/G13R | 10 (23.8) |
Prior treatment, N (%) | |
Surgery | 41 (97.6) |
Radiotherapy | 5 (11.9) |
Medication | 36 (85.7) |
Prior PD-1/PD-L1 inhibitor, N (%) | 17 (40.5) |