Table 3 Differentially methylated regions with rapid weight growth
Gene annotation | ENmix-comb-p | DMRcate | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Genomic coordinates | Gene region | UTR | N | Siddak p-value | Genomic coordinates | Gene region | UTR | N | FDR p-value | |
THEM5 | chr1:151825973-151826205 | Overlaps 5′ | Overlaps 5′ UTR | 4 | 6.75e−08 | chr1:151825974-151826533 | Overlaps 5′ | Overlaps 5′ UTR | 5 | 1.97e−05 |
CLDN4 | chr7:73241728-73242028 | Upstream | - | 4 | 2.65e−07 | chr7:73241729-73242028 | Upstream | - | 4 | 7.02e−05 |
FETUB | chr3:186353574-186353721 | Promoter | - | 2 | 2.65e−07 | chr3:186353350-186353721 | Promoter | - | 3 | 3.01e−04 |
LOXL1-AS1 | chr15:74218696-74218921 | Covers exon(s) | Inside transcription region | 7 | 2.65e−07 | chr15:74218418-74219307 | Covers exon(s) | Inside transcription region | 11 | 1.97e−05 |
PRDM16 | chr1:3239991-3240227 | Inside intron | Inside transcription region | 3 | 2.65e−07 | chr1:3239712-3240227 | Inside intron | Inside transcription region | 4 | 2.85e−04 |
STK10 | chr5:171616387-171616574 | Promoter | - | 3 | 2.65e−07 | chr5:171616388-171616574 | Promoter | - | 3 | 1.03e−04 |
C17orf64 | chr17:58499678-58499911 | Overlaps 5′ | 5′ UTR | 7 | 7.06e−07 | chr17:58499300-58500186 | Overlaps 5′ | Overlaps 5′ UTR | 9 | 1.54e−04 |
TGM3 | chr20:2276434-2276663 | Overlaps 5′ | 5′ UTR | 5 | 8.59e−07 | chr20:2275700-2277040 | Overlaps 5′ | Overlaps 5′ UTR | 8 | 1.93e−04 |
GPX6 | chr6:29454671-29454954 | Upstream | - | 5 | 1.30e−06 | chr6:29454557-29455256 | Upstream | - | 8 | 3.91e−04 |
ACTG1 | chr17:79485528-79485709 | Upstream | - | 2 | 1.33e−06 | chr17:79485529-79485934 | Upstream | - | 3 | 5.59e−04 |
PDE4D | chr5:58883391-58883430 | Inside intron | Inside transcription region | 2 | 1.33e−06 | chr5:58882939-58883430 | Inside intron | Inside transcription region | 3 | 4.03e−04 |
CDHR4 | chr3:49837347-49837654 | Promoter | - | 3 | 2.35e−06 | chr3:49837348-49837689 | Promoter | - | 4 | 8.14e−04 |
SPATA33 | chr16:89734985-89735184 | Inside intron | Inside transcription region | 2 | 2.35e−06 | chr16:89734986-89735184 | Inside intron | Inside transcription region | 2 | 2.54e−03 |
ALOX12-AS1 | chr17:6899296-6899380 | Inside intron | 3′ UTR | 6 | 3.13e−05 | chr17:6898738-6899758 | Inside intron | 3′ UTR | 13 | 1.22e−03 |
AURKC | chr19:57742344-57742421 | Overlaps 5′ | 5′ UTR | 3 | 5.09e−05 | chr19:57741988-57742444 | Overlaps 5′ | 5′ UTR | 9 | 9.22e−04 |
GNMT | chr6:42927939-42927959 | Promoter | - | 2 | 6.49e−03 | chr6:42927940-42928079 | Promoter | - | 7 | 4.31e−03 |