Fig. 1

Diverse differently expressed metabolites between IgG4-RD patients and other matched groups. A The workflow diagram of this study (created with BioRender.com). B ESI+ and ESI− modes of orthogonal partial least-squares discriminant analysis (OPLS-DA) between IgG4-RD patients (including IgG4-RP [n = 24] and IgG4-RSD [n = 22] patients, blue) and other matched groups (PC, n = 24, red; SS, n = 22, green; HC, n = 21, yellow). C ESI+ and ESI− modes of hierarchical clustering between IgG4-RD patients (including IgG4-RP [n = 24] and IgG4-RSD [n = 22] patients, blue) and other matched groups (PC, n = 24, red; SS, n = 22, green; HC, n = 21, yellow). IgG4-RD, immunoglobulin G4-related disease; HC, healthy control; IgG4-RP, IgG4-related pancreatitis; IgG4-RSD, IgG4-related sialadenitis or dacryoadenitis; SS, Sjogren’s syndrome; PC, pancreatic cancer