| Entire | VHSMC cohort | KoGES Consortium | P | ||
---|---|---|---|---|---|---|
KARE cohort | HEXA cohort | CAVAS cohort | ||||
Sample size | 33,879 | 908 | 4,899 | 21,693 | 6,379 | - |
Age (years) | 66.19 ± 8.00 | 73.93 ± 5.93 | 68.50 ± 8.40 | 64.57 ± 7.54 | 68.81 ± 7.67 | <0.001a |
Sex (male %) | 15,332 (45%) | 800 (88%) | 2271 (46%) | 12,117 (56%) | 2685 (42%) | <0.001b |
BMI (kg/m2) | 24.47 ± 3.06 | 25.30 ± 2.89 | 24.85 ± 3.19 | 24.33 ± 3.02 | 24.57 ± 3.12 | <0.001a |
DM (%) | 11,376 (34%) | 777 (86%) | 1916 (39%) | 7158 (33%) | 1525 (24%) | <0.001b |
Hypertension (%) | 10,715 (32%) | 752 (83%) | 1803 (37%) | 6,116 (28%) | 2044 (32%) | <0.001b |
HbA1c (%) | 6.09 ± 1.04 | 7.63 ± 1.74 | 6.22 ± 1.17 | 6.05 ± 1.03 | 5.94 ± 0.85 | <0.001a |
Creatinine (mg/dL) | 0.93 ± 0.42 | 1.61 ± 1.60 | 1.01 ± 0.47 | 0.86 ± 0.39 | 1.00 ± 0.34 | <0.001a |
eGFR (mL/min/1.73 m2) | 76.18 ± 16.80 | 56.12 ± 22.47 | 67.25 ± 15.12 | 82.10 ± 18.24 | 65.78 ± 12.40 | <0.001a |
Uric acid (mg/dL) | 4.98 ± 1.38 | 5.74 ± 1.55 | 5.10 ± 1.45 | 4.92 ± 1.34 | 5.01 ± 1.43 | <0.001a |
Proteinuria | Â | Â | Â | Â | Â | <0.001b |
 No | 29,690 (88%) | 491 (54%) | 4651 (95%) | 19,726 (91%) | 4822 (76%) | - |
 Yes | 2425 (7%) | 403 (44%) | 185 (4%) | 1549 (7%) | 288 (5%) | - |
MLR group (%) | Â | Â | Â | Â | Â | <0.001b |
 Normal | 15,664 (46%) | 72 (8%) | 1968 (40%) | 10,518 (49%) | 3106 (49%) | - |
 Only DM | 8844 (26%) | 330 (36%) | 1459 (30%) | 5978 (28%) | 1077 (17%) | - |
 Only CKD | 6839 (20%) | 59 (7%) | 1015 (21%) | 4017 (18%) | 1748 (27%) | - |
 DKD | 2532 (8%) | 447 (49%) | 457 (9%) | 1180 (5%) | 448 (7%) | - |