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Table 3 Association between average mRNFL thickness and incident CVD in UK Biobank population

From: Retinal nerve fiber layer thinning as a novel fingerprint for cardiovascular events: results from the prospective cohorts in UK and China

RNFL thickness

Model 1

Model 2

HR (95% CI)

p value

HR (95% CI)

p value

Per 5 μm decrease

1.22 (1.14–1.31)

< 0.001

1.08 (1.01–1.17)

0.033

Tertiles

    

 Highest

Reference

−

Reference

−

 Second

1.26 (1.10–1.46)

0.001

1.16 (0.99–1.36)

0.065

 Lowest

1.49 (1.30–1.70)

< 0.001

1.18 (1.01–1.38)

0.036

 P for trend

−

< 0.001

−

0.043

  1. CVD cardiovascular diseases, mRNFL macular retinal nerve fiber layer, HR hazard ratio, CI confidence interval
  2. Model 1 was a univariate model
  3. Model 2 was adjusted for age, sex, ethnicity, assessment center, household income, Townsend deprivation index, SBP, HbA1c, fasting glucose, BMI, smoking status, drinking status, MVPA, history of hypertension and diabetes, antihypertensive drugs, insulin usage, lipid-lowering drugs, IOP, SER, and image quality score
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BMC Medicine

ISSN: 1741-7015

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