Fig. 1
Pregnancy-induced changes in plasma lipidomic profiles. A Sample size and collection time points for maternal plasma samples. B PCA plot of lipidomics data (N = 1595). C Forest plots of three comparative studies using 263 trio subjects (pregnancy vs. preconception, pregnancy vs. postpartum and postpartum vs. preconception). Effect size—log2 of fold change (FC) and error bar—95% confidence interval. Diamond—Padj ≥ 0.05 (grey), circle—Padj < 0.05 and square—Padj < 1.00E−10. The full names of lipid classes refer to Fig. 2C. D Pie charts of percentages of significant lipids in three comparative studies. Colour codes in (D) are consistent with (C)