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Table 1 Demographic, anthropometric and clinical characteristics of the study participants

From: Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study

 

All (N = 976)

Trio subjects (N = 263)

Variable

Preconception

Preconception

Pregnancy

 

Postpartum

n

Mean (Std) or %

n

Mean (Std) or %

n

Mean (Std) or %

n

Mean (Std) or %

Ethnicity

 Chinese

705

72.23%

205

77.95%

205

77.95%

205

77.95%

 Malay

147

15.06%

34

12.93%

34

12.93%

34

12.93%

 Indian

88

9.02%

15

5.70%

15

5.70%

15

5.70%

 Others

36

3.69%

9

3.42%

9

3.42%

9

3.42%

Education

 Below university

363

37.19%

74

28.14%

74

28.14%

74

28.14%

 University & above

612

62.70%

189

71.86%

189

71.86%

189

71.86%

 Missing

1

0.10%

---

---

---

---

---

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Parity

 Nulliparous

630

64.55%

162

61.60%

162

61.60%

162

61.60%

 Parous

344

35.25%

101

38.40%

101

38.40%

101

38.40%

 Missing

2

0.20%

---

---

---

---

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Age at recruitment (years)

976

30.78 (3.73)

263

30.06 (3.26)

263

30.06 (3.26)

263

30.06 (3.26)

Pre-pregnancy BMI (kg/m2)

970

23.78 (5.25)

262

23.03 (4.40)

262

23.03 (4.40)

262

23.03 (4.40)

Breastfeedinga

 Yes

---

---

---

---

---

---

229

87.07%

 No

---

---

---

---

---

---

24

9.13%

 Missing

---

---

---

---

---

---

10

3.80%

Weight (kg)

971

60.71 (13.71)

262

58.75 (11.4)

262

66.66 (11.62)

255

61.69 (11.85)

Gestational weight gainb (kg)

---

---

---

---

261

7.77 (3.88)

---

---

Weight lossc (kg)

---

---

---

---

---

---

253

4.84 (3.54)

Postpartum weight retentiond (kg)

---

---

---

---

---

---

253

2.95 (4.37)

Total cholesterol (mmol/L)

963

4.82 (0.83)

241

4.69 (0.78)

241

6.37 (0.96)

241

5.03 (0.86)

Triglyceride (mmol/L)

962

0.90 (0.50)

241

0.79 (0.35)

241

2.02 (0.63)

241

0.78 (0.36)

HDL cholesterol (mmol/L)

963

1.43 (0.30)

241

1.46 (0.28)

241

1.99 (0.35)

241

1.59 (0.32)

LDL cholesterol (mmol/L)

962

2.97 (0.74)

241

2.87 (0.7)

241

3.46 (0.81)

241

3.09 (0.78)

Fasting glucose (mmol/L)

973

4.81 (0.67)

249

4.73 (0.34)

249

4.27 (0.35)

249

4.56 (0.38)

2-h post-load glucose (mmol/L)

965

5.98 (1.95)

226

5.59 (1.17)

226

6.67 (1.29)

226

5.66 (1.05)

Fasting insulin (mU/mL)

974

7.12 (6.35)

243

5.7 (3.61)

243

7.07 (3.78)

243

4.80 (3.2)

HOMA-IR

971

1.57 (1.66)

240

1.19 (0.78)

240

1.35 (0.76)

240

1.00 (0.72)

HbA1c (%)

973

5.13 (0.42)

249

5.06 (0.27)

249

4.79 (0.29)

249

5.10 (0.28)

  1. BMI body mass index, HDL high-density lipoprotein, LDL low-density lipoprotein, HOMA-IR homeostatic model assessment for insulin resistance, HbA1c glycated haemoglobin
  2. aExclusive breastfeeding at 3 months postpartum
  3. bGestational weight gain: the difference between preconception weight (reference) and the weight at pregnancy (26–28 weeks of gestation)
  4. cWeight loss: the difference between the weight at pregnancy (26–28 weeks of gestation) and the weight at 3 months postpartum (reference)
  5. dPostpartum weight retention: the difference between preconception weight (reference) and the weight at 3 months postpartum