Table 3 Comparisons of patients assigned to 80% and 28% fraction of inspired oxygen during 6 postoperative hours with respect to primary and secondary pre-specified and not pre-specified outcome measures
Outcome measures | 28% FiO2 (n = 99) | 80% FiO2 (n = 94) | p |
|---|---|---|---|
Primary outcome measure | |||
30-day postoperative infections | 23 (23.2%) | 32 (34.0%) | .112 |
Surgical site infections | 15 (15.2%) | 22 (23.4%) | .200 |
Urinary tract infections | 4 (4.0%) | 7 (7.4%) | .363 |
Gastrointestinal infections | 3 (3.0%) | 6 (6.4%) | .321 |
Pneumonia | 2 (2.0%) | 6 (6.4%) | .161 |
Bloodstream infections | 1 (1.0%) | 1 (1.1%) | > .999 |
Cardiovascular system infections | 0 (0.0%) | 1 (1.1%) | .487 |
Other | 0 (0.0%) | 2 (2.1%) | .236 |
Secondary outcome measures | |||
90-day patient mortality rate | 5 (5.1%) | 4 (4.3%) | > .999 |
90-day severe morbidity rate | 28 (28.3%) | 41 (43.6%) | .035 |
Early allograft dysfunction | 30 (30.3%) | 36 (38.3%) | .288 |
Post-transplant hospital stay (days) | 17.5 (0.7) | 19.1 (0.7) | .113 |
Post-transplant ICU stay (days) | 5.4 (0.2) | 6.6 (0.4) | .033 |
30-day pulmonary complication rate | 25 (25.3%) | 29 (30.9%) | .425 |
Other (not pre-specified) | |||
Comprehensive complication indexa | 22.6 (8.7–45.7) | 24.2 (12.2–48.1) | .060 |
Post-reperfusion syndromeb | 22 (22.2%) | 30 (31.9%) | .146 |
Acute kidney injuryc | 46 (46.5%) | 54 (57.4%) | .150 |
Need for pressure support | 11 (11.1%) | 10 (10.6%) | > .999 |