Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

Table 3 Correlations between the mRNA levels of DUSPs in peripheral T cells with disease activity in patients with ankylosing spondylitis

	DUSP4		DUSP5		DUSP6		DUSP7		DUSP14		DUSP22
	r	p value	r	p value	r	p value	r	p value	r	p value	r	p value
Inflammatory markers
ESR (mm/h)	0.220	0.121	0.208	0.143	0.221	0.099	0.310	0.038^*	0.218	0.104	−0.501	< 0.001^*
CRP (mg/dL)	0.093	0.517	0.072	0.615	0.184	0.171	0.141	0.357	0.101	0.454	−0.369	0.005^*
Disease activity
BASDAI	0.145	0.354	0.190	0.223	0.177	0.223	0.156	0.356	0.140	0.338	−0.343	0.016^*
BASFI	0.099	0.529	0.103	0.510	0.103	0.481	0.074	0.662	−0.010	0.944	−0.231	0.110
BAS-G	−0.138	0.377	−0.068	0.664	0.022	0.882	−0.172	0.308	−0.126	0.390	−0.206	0.156
mSASSS	0.083	0.566	0.032	0.826	−0.046	0.738	0.009	0.954	0.080	0.560	−0.024	0.860

Abbreviation: BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BASFI BAS Functional Index, BAS-G BAS Patient Global Score, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, h hour, mSASSS the modified Stoke Ankylosing Spondylitis Spinal Score
*Significant p value (< 0.05)

ISSN: 1741-7015