Fig. 3

Representing the molecular interaction between vaccine construct and host TLRs receptors that help to activate and trigger innate immune responses resulting in enhancing the potential protective immune response of the host. The complex interaction of the vaccine (V) constructs with the host viral recognition receptors TLRs has been depicted after molecular docking. Herein, showing the interactions between A TLR3 and vaccine construct 2 (TLR3-V2), B TLR8 and vaccine construct 2 (TLR8-V2), C TLR4 and vaccine construct 1 (TLR4-V1). The cartoon structures of proteins represent the TLRs receptors, whereas the ball shape of the protein represents the vaccine constructs