Table 4 Validation of the V1 and V2 vaccine structure through Ramachandran and z-score
Vaccine | Residue covered region | Crude | Refine |
|---|---|---|---|
V1 vaccine | Residues in most favored regions [A, B, L] | 92.40% | 94.60% |
Residues in additional allowed regions [a, b, l, p] | 6.30% | 4.00% | |
Residues in generously allowed regions [~ a, ~ b, ~ l, ~ p] | 0.40% | 0.00% | |
Residues in disallowed regions | 0.90% | 1.30% | |
z score |  − 3.44 |  − 3.73 | |
V2 vaccine | Residues in most favored regions [A, B, L] | 87.50% | 92.90% |
Residues in additional allowed regions [a, b, l, p] | 9.50% | 6.00% | |
Residues in generously allowed regions [~ a, ~ b, ~ l, ~ p] | 3.00% | 0.00% | |
Residues in disallowed regions | 0.00% | 1.20% | |
z score |  − 2.93 |  − 2.89 |