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Table 6 Docking score between V1 and TLR4 receptor, V2 and TLR3 receptor, and V2 and TLR8 receptor

From: In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever

Vaccine complex

Representative

Weighted score

TLR-3 complex (TLR3-V2)

Centre

 − 1089

Lowest energy

 − 1258.7

TLR-4 complex (TLR4-V1)

Centre

 − 1001.4

Lowest energy

 − 1166.3

TLR-8 complex (TLR8-V2)

Centre

 − 1106.2

Lowest energy

 − 1342.5