Gene | SNP | A1/A2 | eQTL association | GWAS association | SMR association | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta | Se | P value | F | Outcome | Beta | Se | P value | OR (95% CI) | P value | |||
GLP1R | rs2268650 | A/G | −0.42 | 0.06 | 2.26×10−12 | 49.25 | DR | 0.01 | 0.01 | 0.34 | 0.97 (0.92–1.03) | 0.3471 |
GLP1R | rs2268650 | A/G | −0.42 | 0.06 | 2.26×10−12 | 49.25 | Background DR | 0.08 | 0.03 | 0.01 | 0.83 (0.71–0.97) | 0.0162 |
GLP1R | rs2268650 | A/G | −0.42 | 0.06 | 2.26×10−12 | 49.25 | Severe nonproliferative DR | 0.14 | 0.06 | 0.03 | 0.72 (0.53–0.98) | 0.0355 |
GLP1R | rs2268650 | A/G | −0.42 | 0.06 | 2.26×10−12 | 49.25 | Proliferative DR | 0.01 | 0.02 | 0.52 | 0.98 (0.91–1.05) | 0.5256 |