Fig. 3

Enriched pathways in neutrophils. A Venn diagram represents all enriched pathways in neutrophils at 0–24 h, 24–48 h, and >48 h (Fisher’s p-value<0.05). Fourteen pathways overlapped all time points. B Top 10 common pathways enriched in all three time points. C Top over-represented pathways with predicted activation (z≥ 2, orange shades) or inhibition (z≤ −2, blue shades) at every time point. D Top 10 over-represented pathways unique for each time point (Fisher’s p-value<0.05). Down arrows indicate predicted significant inhibition (z≤ −2) and up arrows predicted significant activation (z≥ 2). Blue cells indicate negative z-score, and orange positive z-score. White cells indicate no direction can be predicted, and grey indicate that no prediction can be performed (*= Benjamini–Hochberg-corrected p-value<0.05). Reg: regulation