Fig. 5

Anti-sporozoite IgG titers. IgG antibody titers against sporozoite extract in sera of cohort A participants immunized with three times fifteen PfNF135-infected mosquitoes (purple, n = 10) and of participants in a historical comparator trial immunized with three times fifteen PfNF54-infected mosquitoes (blue, n = 12), at baseline, after the first immunization, and after completion of the course of three immunizations. Thick and thin horizontal lines represent median and interquartile range, respectively. The Mann–Whitney U test was used for differences between studies. Friedman test with post hoc paired comparison using Bonferroni-corrected Wilcoxon signed rank test was used for comparisons of time points within studies