From: Whole sporozoite immunization with Plasmodium falciparum strain NF135 in a randomized trial
High dose | Low dose | |
---|---|---|
Infectious mosquitoes per immunization | 15 | 5 |
Parasitemia on day 7 post-immunization | ||
Immunization 1 | 22,614 (1–91,365)1 | 6181 (2339–20,579)2 |
Immunization 2 | 1 (1–1358)3 | 1 (1–1738)4 |
Immunization 3 | 57 (1–233,451)3 | 573 (1–8626)4 |
Peak parasitemia following each immunization | ||
Immunization 1 | 40,535 (1–174,050)1 | 65,550 (12,376–1,038,721)2 |
Immunization 2 | 1 (1–686,606)3 | 1 (1–1,670,962)4 |
Immunization 3 | 2536 (1–552,676)3 | 20,649 (1–5,021,767)4 |