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Table 1 Demographic information pertaining to subjects used for the aptamer-based screen

From: Comprehensive proteomics and platform validation of urinary biomarkers for bladder cancer diagnosis and staging

Variable

Category

UC

(N = 15)

Ta

(N = 5)

Tis

(N = 4)

T1

(N = 9)

T2–T4

(N = 9)

 Agea

 

66.2 ± 4.1

66.6 ± 12.1

68.5 ± 4.7

69.3 ± 10.1

71.9 ± 12.4

 Gender, n (%)

Male

15 (100.0%)

5 (100.0%)

4 (100.0%)

9 (100%)

9 (100%)

 Ethnicity, n (%)

Caucasian

6 (40.0%)

4 (80.0%)

4 (100.0%)

5 (55.6%)

5 (55.6%)

Others

1 (6.6%)

N/A

N/A

N/A

N/A

Unknown

8 (53.3%)

1 (20.0%)

N/A

4 (44.4%)

4 (44.4%)

Demographic information pertaining to the ELISA validation cohort (UTSW cohort)

Variable

Category

UC

(N = 31)

Ta

(N = 10)

Tis

(N = 10)

T1

(N = 10)

T2–T4

(N = 7)

 Agea

 

66.2 ± 10.1

71.3 ± 11.9

71.5 ± 6.3

67.4 ± 9.9

74.3 ± 7.9

 Gender, n (%)

Male

27 (87.1%)

8 (80%)

10 (100%)

8 (80%)

7 (100%)

Female

4 (12.9%)

2 (20%)

N/A

2 (20%)

N/A

 Ethnicity, n (%)

Caucasian

23 (74.2%)

8 (80%)

9 (90%)

8 (80%)

6 (85.7%)

Black

4 (12.9%)

N/A

N/A

1 (10%)

1 (10%)

Asian

2 (6.5%)

1 (10%)

N/A

1 (10%)

N/A

Hispanic

N/A

1 (10%)

N/A

N/A

N/A

Others

1 (3.2%)

N/A

N/A

N/A

N/A

Unknown

1 (3.2%)

N/A

1 (10%)

N/A

N/A

  1. Top: Demographic information pertaining to the 42 subjects included in the aptamer-based screen. NMIBC comprised Ta, Tis, and T1 subjects. MIBC comprised T2–T4 BC. Subjects in the UC category comprised of BPH (n = 1), elevated PSA (n = 1), erectile dysfunction (n = 2), HLD (n = 2), allergic rhinitis (n = 2), hypothyroidism (n = 2), dementia (n = 1), insomnia (n = 1), impotence (n = 1), osteopenia (n = 1), thrombocytopenia (n = 1), hemangioma (n = 1), glaucoma (n = 1), and gout (n = 1)
  2. Bottom: Demographic information pertaining to the 68 subjects used for the independent ELISA validation cohort UTSW Cohort. NMIBC comprised Ta, Tis, and T1 subjects. MIBC comprised T2–T4 BC. UC subjects comprised patients with various urological conditions including bladder diverticulum (n = 1), bladder stones (n = 1), BPH (n = 7), cystocele (n = 1), elevated PSA (n = 2), erectile dysfunction (n = 3), hematuria (n = 3), UTI (n = 1), hydrocele (n = 1), incomplete bladder emptying (n = 1), impotence (n = 1), kidney stones (n = 3), nocturia (n = 2), prostate cancer (n = 1), and stress incontinence (n = 1)
  3. aAge displayed as mean ± standard deviation