Adverse birth outcomes and early-life infections after in utero exposure to corticosteroids for inflammatory bowel disease: a Danish nationwide cohort study

Table 2 The hazard ratio of congenital malformations in live born children exposed in utero to corticosteroids (#1), relative to children not exposed in utero to corticosteroids. Multivariable Cox proportional hazard regression model with crude and adjusted estimates with 95% confidence intervals (CI)

	Live births after in utero exposure to corticosteroids #1 N=707		Live births not exposed in utero to corticosteroids N=9371		Odds ratio (95% CI)
	N events	Years at risk	N events	Years at risk	Crude	Adjusted^a
Congenital malformations	37	673.6	374	9021.8	1.32 (0.94–1.85)	1.28 (0.82–2.00)

^aAdjusted for maternal comorbidity, maternal age at child birth, calendar year of child birth, maternal smoking status, parity, sex of the child, maternal BMI, maternal use of biologic therapy, azathioprines, or 5-ASA 30 days prior to conception or during pregnancy

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