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Fig. 2 | BMC Medicine

Fig. 2

From: Downregulation of AC092894.1 promotes oxaliplatin resistance in colorectal cancer via the USP3/AR/RASGRP3 axis

Fig. 2

Ectopic overexpression of AC092894.1 promotes chemosensitivity of CRC cells to oxaliplatin. A RT-qPCR assay for stable overexpression of AC09894.1. B, C Overexpression of AC092894.1 on cells detected by CCK-8 after treatment with the indicated concentrations of oxaliplatin for 48 h. D The effect of AC092894.1 overexpression on apoptosis detected by flow cytometry after 5 μg/ml oxaliplatin treatment for 48 h. E Statistical analysis of apoptosis rates. F The influence on colony formation by overexpression of AC092894.1 was examined after treatment with oxaliplatin (5 μg/ml) for 48 h. G Counting and statistical analysis of the colony numbers. I Western blotting to detect the expression of C-PARP in cell lysates with GAPDH as a control

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BMC Medicine

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