Fig. 7
AC098894.1 promotes oxaliplatin sensitization of drug-resistant CRC cells in vivo. A Nude mice were subcutaneously xenografted with HCT116-OxR cells (4 × 106 cells) and injected intraperitoneally with oxaliplatin (5 mg/kg/day per mouse) or DMSO every 5 days. B Tumor weighing analysis. C Tumor growth curves for each group. Data were subjected to Student’s t-test. D RT-qPCR assays for the expression of AC092894.1 in each group of tumors. E Representative IHC images showing p-p38 expression in tumors from each group of mice