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Table 1 Baseline characteristics according to EAT thickness

From: Association between epicardial adipose tissue and incident heart failure mediating by alteration of natriuretic peptide and myocardial strain

 

Overall

EAT < 9 mm

EAT ≥ 9 mm

P

N  = 1554

N  = 785

N  = 769

EAT, mm

9.8 (6.0)

5.3 (2.6)

14.4 (4.8)

 < 0.001

Female, N

824 (53.0)

482 (61.4)

342 (44.5)

 < 0.001

Age, years

63.3 (8.9)

62.6 (9.0)

64.1 (8.8)

0.002

BMI, kg/m2

28.1 (5.1)

26.8 (4.9)

29.4 (5.0)

 < 0.001

SBP, mmHg

128.0 (16.7)

126.5 (16.6)

129.4 (16.7)

0.001

DBP, mmHg

73.6 (9.9)

73.5 (9.4)

73.7 (10.3)

0.72

eGFR, mL/(mL/min/1.73m2)

79.2 (16.4)

79.5 (15.4)

78.9 (17.5)

0.44

Heart rate, bpm

61.9 (10.1)

61.1 (10.0)

62.7 (10.3)

0.002

Triglycerides, mg/dL

114.9 (61.7)

105.0 (54.6)

125.0 (66.8)

 < 0.001

LDL-c, mg/dL

106.8 (31.1)

108.2 (29.2)

105.4 (32.9)

0.07

HDL-c, mg/dL

57.6 (17.8)

61.0 (17.9)

54.1 (17.0)

 < 0.001

FBG, mg/dL

105.5 (22.6)

102.5 (19.4)

108.5 (25.2)

 < 0.001

Comorbidities, N

 Diabetes mellitus

186 (12.0)

69 (8.8)

140 (18.2)

 < 0.001

 Atrial fibrillation

63 (4.1)

28 (3.6)

35 (4.6)

0.39

 Coronary heart disease

116 (7.5)

45 (5.7)

71 (9.2)

0.011

 Dyslipidemia

1076 (69.2)

491 (62.5)

585 (76.1)

 < 0.001

Medications, N

 ACEI/ARB

473 (30.4)

182 (23.2)

291 (37.8)

 < 0.001

 Beta-blocker

378 (24.3)

174 (22.2)

204 (26.5)

0.06

 CCB

184 (11.8)

78 (9.9)

106 (13.8)

0.023

 Diuretic

293 (18.9)

127 (16.2)

166 (21.6)

0.008

 Statin

559 (36.0)

253 (32.2)

306 (39.8)

0.002

 Antiplatelet agent

634 (40.8)

316 (40.3)

318 (41.4)

0.70

 Antidiabetic agent

115 (7.4)

37 (4.7)

78 (10.1)

 < 0.001

Cardiac measures

 LVEDD, mm

50.6 (4.7)

50.0 (4.6)

51.1 (4.7)

 < 0.001

 LAID, mma

30.2 (5.3)

28.8 (5.0)

31.6 (5.2)

 < 0.001

 LVWT (septal), mm

7.9 (1.4)

7.6 (1.3)

8.1 (1.4)

 < 0.001

 LVWT (inferior), mm

6.8 (1.3)

6.5 (1.2)

7.0 (1.3)

 < 0.001

 LVEF, %

67.3 (6.7)

67.2 (6.0)

67.5 (7.3)

0.37

 GLS, %a

 − 20.6 (3.3)

 − 21.1 (3.2)

 − 20.2 (3.4)

 < 0.001

 E/é a

7.0 (2.2)

6.9 (2.1)

7.2 (2.3)

0.005

  1. Presented as number (percentage) or mean (SD)
  2. Abbreviations: EAT epicardial adipose tissue, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, eGFR estimated glomerular filtration rate, HDL-c high-density lipoprotein cholesterol, LDL-c low-density lipoprotein cholesterol, FBG fasting blood glucose, ACEI angiotensin-converting enzyme inhibitor, ARB angiotensin receptor blocker, CCB calcium channel blockers, LVEDD left ventricular end-diastolic dimension, LAID left atrial internal dimension, LVWT left ventricular wall thickness, LVEF left ventricular ejection fraction, GLS global longitudinal strain
  3. aMissing values existed in LAID, GLS, and E/é (56, 95, and 70, respectively)