Fig. 8From: Helicobacter pylori-induced aberrant demethylation and expression of GNB4 promotes gastric carcinogenesis via the Hippo–YAP1 pathwaySchematic illustration of the molecular mechanism of GNB4 in H. pylori-induced GC. H. pylori induces GNB4 upregulation via the NF-κB-TET1 axis. TET1-mediated demethylation of GNB4 promoter leads to the transcriptional activation of GNB4, and high GNB4 expression contributes to GC progression via the Hippo–YAP1 pathwayBack to article page