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Table 1 Demographic, clinical characteristics, and risk factors of the patients included

From: Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population

Characteristics

Discovery stage

Replication stage

 

Case

Control

Case

Control

 

N = 622

N = 8853

N = 646

N = 8810

Demographic characteristics

 Age, year, mean (SD)

62 (19)

59 (9)

62 (15)

59 (8)

 Male, n (%)

323 (52)

4041 (46)

341 (53)

4041 (46)

 BMI, kg/m2, mean (SD)

24.4 (3.9)

-

24.5 (3.6)

-

 PE alone, n (%)

331 (53)

-

340 (53)

-

 PE combined DVT, n (%)

291 (47)

-

306 (47)

-

Complications and risk factors

 

-

 

-

 Cardiovascular disease, n (%)

311 (50)

-

311 (48)

-

 Chronic pulmonary disease, n (%)

105 (17)

-

118 (18)

-

 Cancer, n (%)

60 (10)

-

62 (10)

-

 Metabolic and endocrine diseases, n (%)

108 (17)

-

101 (16)

-

 Smoking history, n (%)

198 (32)

-

182 (28)

-

 

N = 218

 

N = 220

 

Thrombophilia test

 

-

 

-

 Plasma antithrombin activity < 70%, n/N (%)

32 (15)

-

32 (15)

-

 Plasma protein S activity < 60%, n/N (%)

36 (17)

-

42 (19)

-

 Plasma protein C activity < 70%, n/N, n/N (%)

42 (19)

-

49 (22)

-

  1. BMI Body mass index, PE Pulmonary embolism, SD Standard deviation