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Fig. 6 | BMC Medicine

Fig. 6

From: Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

Fig. 6

SF-mediated transcription factors upregulate MMP13. A Expression of hucMSC transcription factors treated with SF. B Expression of hucMSCs treated with SF and p65-SiRNA. C Expression of hucMSCs treated with SF and c-Fos-SiRNA. D Expression of hucMSCs treated with SF and c-Jun-SiRNA. E Expression of chondrocytes treated with hucMSCs (with c-Jun knockdown) and SF. Values are presented as mean ± SD. The different letter symbols (a, ab, b, bc, c, cd, bcd, d, and e) indicate significant difference between each other (Fisher's LSD, P < 0.05 or P < 0.01) in descending order of data from a to z, in which the overlapped letters (e.g., b versus bc, c versus cd, and cd versus d) were statistically but not significantly differed. All experiments were repeated at least three times

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BMC Medicine

ISSN: 1741-7015

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